Celgene Senior Associate Scientist, Pharmacology - In vivo in Massachusetts, United States

Description

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Summary/Scope:

We are seeking a highly motivated Sr. Associate Scientist with strong interpersonal communication skills to work in a small pharmacology group under the direction of a Sr. Scientist to design and conduct in vivo short term pharmacology models of inflammation, as well as to establish early PK/PD for lead progression. The candidate will be able to organize and implement rodent studies, summarize data, and with mentorship, present to discovery teams.

Responsibilities will include, but are not limited to, the following:

  1. Design and conduct in vivo studies in rodents to establish PK/PD relationships, and in vivo proof of concept for target validation in a dynamic, fast-paced discovery environment.

  2. Directly enable the conduct of in vivo studies. Demonstrated expertise in small animal handling, dosing, recording of observations, blood and tissue collection and necropsy required.

  3. Ability to prepare dose formulations including calculation of dose amounts/volumes and the ability to prepare routine formulations.

  4. Data collection in electronic notebook or in hardcopy laboratory notebooks is critical.

  5. Communicate effectively within the Preclinical Sciences group, which includes colleagues in PK/bioanalysis.

Qualifications

Requirements:

  • Bachelor’s degree in a scientific discipline with at least 8 years work experience or Master’s degree in a scientific discipline with at least 6 years work experience, both with some training in pharmacology/toxicology or animal science.

  • BS/MS degree in a life science with some training in pharmacology/toxicology or animal science.

  • Experience with design and execution of rodent pharmacology studies, including hands on laboratory experience in small animal experimentation is required.

  • This candidate has to be proficient in handling rodents (rats, and mice) and able to calculate dose formulations, prepare formulations, administer compounds via various routes(IV, PO, IP), and collect blood and various tissue samples for analysis.

  • Also, this candidate should be proficient in data collection/documentation, either in electronic or hardcopy forms.

  • This individual is also expected to be highly organized, detail oriented, a team player, enthusiastic about drug discovery, and a strong communicator with a strong work ethic.

Skills/Knowledge Required:

  • Experience in in vivo study conduct;animal handling, husbandry, dosing by multiple routes, observation recording, blood, tissue collection and limited necropsy.

  • Ability to generate protocols, and record data in a notebook (electronic or hardcopy)

  • Ability to generate high quality data in a dynamic high paced environment

Skills/Knowledge Desired:

  • Knowledge of rodent models of immunology/inflammation

Personal characteristics:

  • Strong presence as well as sense of urgency and priorities as well as flexibility. The ability and strong desire to "make things happen".

  • Decisive as well as collaborative.

  • High level of honesty and integrity.

  • Excellent interpersonal skills with particular emphasis on communication & relationship building.

  • Motivated to be part of an organization that aims to make a difference through cutting edge research.

  • Passion for the pharmaceutical industry.

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.

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BIO-US

Senior Associate Scientist, Pharmacology - In vivo

Location: Massachusetts, , US

Job ID: 17001098